GWR may refer to:
Transport
- Great Western Railway, former British railway company (1833–1947)
- Great Western Railway (train operating company), British railway company (1996–)
- Great Western Main Line, a railway line in the UK
- Great Western Railway (disambiguation), other railway companies and routes with the name
- Gloucestershire Warwickshire Railway, an English heritage railway
- Aura Airlines (ICAO airline code: <code>GWR</code>), a Spanish airline
- Gwinner–Roger Melroe Field (FAA airport code: <code>GWR</code>), Sargent County, North Dakota, USA
Media
- GWR Group, a defunct British commercial radio company, merged into GCap Media in 2005
- GWR FM (Bristol & Bath)
- GWR FM Wiltshire
- GWR Records, a British record label
- Graswurzelrevolution, a German anarcho-pacifist magazine
Other uses
- Geographically weighted regression
- Gwere language (ISO 639 language code: <code>gwr</code>)
- Llygad Gŵr, 13th-century Welsh poet
- Guinness World Records