GPT may refer to:
Computing
- Generative pre-trained transformer, a type of large language model that is widely used in generative artificial intelligence chatbots
- ChatGPT, a generative artificial intelligence chatbot developed by OpenAI
- GUID Partition Table, a computer data storage partitioning standard
Biology
- Alanine transaminase, or glutamate pyruvate transaminase, a mammalian protein
- Goniopora toxin, a polypeptide toxin
- UDP-N-acetylglucosamine—undecaprenyl-phosphate N-acetylglucosaminephosphotransferase, a class of enzymes
Companies
- GEC Plessey Telecommunications, a defunct British telecommunications manufacturer
- GPT Group, an Australian property investment company
- GPT, a subsidiary of Airbus
- Baby Badger GPT, AI-driven optimization tools from Content Pathway
Other uses
- General-purpose technology, in economics
- Generalized probabilistic theory, a framework to describe the features of physical theories
- Grounded practical theory, a social science theory
- "GPT", a song on the album ...l, by the Korean girl group STAYC
- Hack-GPT, a fictional AI chatbot that appears in The Simpsons episode, Bart's Birthday
- Gulfport–Biloxi International Airport, United States (IATA code: GPT)