Fred Rosen (physician)

Fred Saul Rosen (May 25, 1930 – May 21, 2005) was a pediatrician and immunologist at Harvard Medical School and Boston Children's Hospital.

Early life and career

Rosen was born in Newark, NJ. He received his bachelor's degree from Lafayette College and his MD from Case Western Reserve University. He moved to Boston in 1955 to begin a pathology residency at Children's where he worked with Charles Janeway and Sidney Farber. He began an immunology fellowship in 1959. He and Janeway pioneered the study of primary immunodeficiency diseases at Boston Children's Hospital.

Rosen discovered, early in his career, the cause of X-linked hyper-IgM syndrome. He also worked on X-linked agammaglobulinaemia. He published over 300 papers on his research. In 1987, he moved to the CBR Institute for Biomedical Research at Harvard University.