The Fortymile River is a tributary of the Yukon River in the U.S. state of Alaska and the Canadian territory of Yukon. After the gold discovery, two Alaska Commercial Company traders, Jack McQuesten and Arthur Harper, built a post at the mouth of the river.

Between 1968 and 1978, Cassiar Mining extracted about a million metric tons of asbestos from three open pits along Clinton Creek, a tributary of lower Fortymile River in the Yukon. After abandoning the site, the company went bankrupt in 1992, and the territorial and Canadian governments and others removed or buried mine wastes, stabilized the creek banks, and worked to partly restore the land. This included designated "wild", called "scenic", and designated "recreational".

Climate

Boating

The Fortymile River main stem as well as the North Fork, South Fork, and other tributaries offer a variety of boating possibilities for experienced paddlers of rafts and kayaks, or experienced canoeists willing to portage around difficult rapids. The many runnable segments vary from Class I (easy) on the International Scale of River Difficulty to Class V (extremely difficult). In addition to rapids, dangers include overhanging or submerged vegetation and the high probability of confusing one bend in a stream with another—thus entering rapids disoriented and unprepared—without the aid of a map and compass.