Fort St. Joseph may refer to:
;In Canada:
- Fort St. Joseph (Ontario), on St. Joseph Island at southern end of the St. Marys River, now the site of Fort St. Joseph National Historic Site Canada
;In the United States:
- Fort St. Joseph (Port Huron), on north end of the St. Clair River in what is now Port Huron, Michigan
- Fort St. Joseph (Niles, Michigan), on the St. Joseph River near what is now Niles, Michigan
;Other
- Fort-Liberté, previously known as Fort St. Joseph, in Haiti
- Fort St. Joseph, Bakel, Senegal