Esashi may refer to:
Places in Japan
- Esashi District, Hokkaidō, a district in Sōya Subprefecture, Hokkaidō
- Esashi, Hokkaidō (Hiyama), the capital town of Hiyama Subprefecture, Hokkaidō
- Esashi, Hokkaidō (Sōya), a town in Esashi District, Sōya Subprefecture, Hokkaidō
- Esashi, Iwate, previously a city, now a ward in Ōshū city, Iwate Prefecture
- Esashi District, Iwate, a district located in Iwate Prefecture
- Esashi Station a railway station on the Esashi Line
- Esashi Line a Japanese railway line
- Esashi Town Historical Museum
People with the surname
- , Japanese engineer
Others
- Esashi oiwake music, a folk song from Hokkaidō