Eastern Shore may refer to:
- Regions in the Delmarva Peninsula:
- Eastern Shore of Maryland
- Eastern Shore of Virginia
- Eastern Shore (Nova Scotia), a region
- Eastern Shore (electoral district), a provincial electoral district in Nova Scotia
- Eastern Shore (Alabama), of Mobile Bay
- , a United States Navy cargo ship in commission from 1918 to 1919
- University of Maryland Eastern Shore, University in Princess Anne, Maryland
See also
- East Shore (disambiguation)