EKU or Eku may refer to:
Businesses and organisations
- Eastern Kentucky University, Richmond, United States (founded 1906)
- European Karate Union (now Federation; founded 1966)
- Evangelical Church of the Union, a German Christian denomination (1953–2004; )
- EKU, a German beer brand of Kulmbacher Brewery
Other uses
- Eku, Delta, a town in Nigeria
- Earliest known use, of a postage stamp
- Extended Key Usage, in public key infrastructure
- Eku Edewor (born 1986), Brirish-Nigerian actress