As of the census of 2000, there were 159 people, 72 households, and 47 families residing in the town. The population density was . There were 231 housing units at an average density of . The racial makeup of the town was 98.11% White, 0.63% Native American, 1.26% from other races. Hispanic or Latino of any race were 1.26% of the population.

There were 72 households, out of which 20.8% had children under the age of 18 living with them, 55.6% were married couples living together, 6.9% had a female householder with no husband present, and 34.7% were non-families. 29.2% of all households were made up of individuals, and 6.9% had someone living alone who was 65 years of age or older. The average household size was 2.21 and the average family size was 2.70. The name is that of James Duane.

In the town, the population was spread out, with 17.0% under the age of 18, 3.8% from 18 to 24, 24.5% from 25 to 44, 35.2% from 45 to 64, and 19.5% who were 65 years of age or older. The median age was 47 years. For every 100 females, there were 98.8 males. For every 100 females age 18 and over, there were 100.0 males.

The median income for a household in the town was $37,500, and the median income for a family was $38,750. Males had a median income of $29,500 versus $21,458 for females. The per capita income for the town was $19,130. About 10.2% of families and 14.5% of the population were below the poverty line, including 21.4% of those under the age of eighteen and none of those 65 or over.

Communities and locations in Duane

  • Clear Pond – A lake north of Meacham Lake.
  • Deer River – A stream flowing northward from the town.
  • Deer River Flow – A lake formed on the Deer River near the northern town line.
  • Duane Center – A hamlet in the north-central part of the town on County Road 26, west of NY-30.
  • Meacham Lake – A lake by the southern town line next to NY-30, named after Thomas Meacham.
  • Meacham Lake Campground – A public camping area at the northern end of Meacham Lake.
  • Debar Pond Lodge – A former Great Camp on Debar Pond.

Climate

The Köppen Climate Classification sub-type for this climate is "Dfb" (Warm Summer Continental Climate).

References