Diocese of Chicago may refer to:
;Catholic
- Roman Catholic Archdiocese of Chicago
- St. Thomas Syro-Malabar Catholic Diocese of Chicago
- Ukrainian Catholic Eparchy of Chicago
;Orthodox
- Diocese of Chicago and Mid-America (ROCOR)
- Metropolis of Chicago (Patriarchate of Constantinople)
- Orthodox Church in America Diocese of the Midwest (cathedra in Chicago)
;Anglican
- Episcopal Diocese of Chicago
;Lutheran
- Metropolitan Chicago Synod