Despair is a state of depressed mood and hopelessness.

Despair may also refer to:

  • Despair (sculpture), a c. 1890 sculpture by Auguste Rodin
  • Despair (novel), a 1936 novel by Vladimir Nabokov
  • Despair (film), a 1978 film adaptation by Rainer Fassbinder
  • Despair, a 1969 underground comic by Robert Crumb
  • Despair (DC Comics), a character in the Sandman comic book series
  • Giant Despair, a character in The Pilgrim's Progress by John Bunyan
  • Despair, Inc., a company that makes satirical posters and souvenirs
  • Despair (band), a thrash metal band
  • Despair (album), an album by Omar Rodríguez-López
  • "Despair", a song by the Yeah Yeah Yeahs from their studio album Mosquito, 2013
  • Neka mi ne svane, Croatian Eurovision Song Contest entry from 1998, also known as "Despair".
  • Mount Despair (disambiguation), several mountains

See also

  • Diseases of despair
  • Desperate (disambiguation)