Clarksburg may refer to the following places:
;Canada
- Clarksburg, Ontario, a community of The Blue Mountains, Ontario
;United States of America
- Clarksburg, California
- Clarksburg AVA, an American Viticultural Area
- Clarksburg, former name of Clarksville, California
- Clarksburg, Indiana
- Clarksburg, Kentucky in Lewis County along Kentucky Route 10
- Clarksburg, Maryland
- Clarksburg, Massachusetts
- Clarksburg, Michigan
- Clarksburg, Missouri
- Clarksburg, New Jersey
- Clarksburg, New York
- Clarksburg, Ohio
- Clarksburg, Pennsylvania
- Clarksburg, Tennessee
- Clarksburg, West Virginia
See also
- Clarkstown, New York
- Clarksville (disambiguation)