Cholon may refer to:
- Chợ Lớn, or Cholon, a quarter of Ho Chi Minh City, Vietnam
- Chợ Lớn, Ho Chi Minh City, a ward of the city within the Chợ Lớn quarter
- Chợ Lớn province, a former province of South Vietnam
- Cholón District, a district of Marañón, Peru
- Cholón language, also known as Seeptsá and Tsinganeses, a recently extinct language of Peru