The Cathedral of the Immaculate Conception in Syracuse, New York, in the United States is the mother church of the Roman Catholic Diocese of Syracuse. It is the seat of the bishop of Syracuse; as of 2026, the bishop is Douglas Lucia.
History
The precursor of Immaculate Conception Cathedral was St. Mary's Church, built in Syracuse in 1874 by Lawrence J. O'Connor. In 1887, the Vatican erected the Diocese of Syracuse and appointed Patrick Anthony Ludden as its first bishop. Using his own funds, Ludden purchased property next to St. Mary's Church to expand the church into a cathedral. He commissioned the architect Archimedes Russell to design a new sanctuary and bell tower.
The Cathedral of the Immaculate Conception was consecrated in 1910.
The Shrine of the Blessed Mother is located in the cathedral. It features a statue sculpted by Jacqueline Belfort-Chalat.
Ministries
thumb|250px|Interior, Immaculate Conception Cathedral (2025)
The Cathedral Emergency Services operates a food pantry in downtown Syracuse. Amaus Health Services at the cathedral offers dental and vision services to the poor and uninsured.
Music
The cathedral hosts local musicals and concerts performed by both area high schools, colleges, and professional groups. A selection of works by Herbert Howells played on the cathedral's 1892 Roosevelt-Schantz organ has been released on CD.