A canebrake is a thick, dense growth of cane or sugarcane.

Canebrake may also refer to:

;Places in the North America:

  • Canebrake (region of Alabama)
  • Canebrake, California, an unincorporated community in Kern County, California
  • Canebrake Ecological Reserve in Kern County, California
  • Canebrake Canyon, California in San Diego County, California
  • Canebrake (Ferriday, Louisiana), in Concordia Parish, listed on the NRHP in Louisiana
  • Canebrake, Mississippi, a subdivision and golf course in Lamar County, Mississippi
  • Canebrake, South Carolina in Greenville County, South Carolina
  • Cane Brake in Edgefield County, South Carolina
  • Canebrake, Tennessee in Rutherford County, Tennessee
  • Canebrake, West Virginia in McDowell County, West Virginia
  • Canebreak Branch in Anson County, North Carolina
  • Cape Canaveral, a town in Brevard County, Florida, or "Canebrake", translated from the original Spanish Cañaveral

;Animals:

  • Canebrake groundcreeper, a species of ovenbird
  • Canebrake rattlesnake, a species of venomous pit viper
  • Canebrake tree frogs, a genus of tree frog
  • Canebrake wren or plain wren, a species of wren