COTS may refer to:
- Commercial off-the-shelf, products that are commercially available and can be bought "as is"
- Commercial Orbital Transportation Services, a NASA program for delivery to the International Space Station by private companies
<!--* Connection Oriented Transport Service, see Connection-oriented communication (fails WP:DABMENTION WP:DABACRO)-->
- Crown-of-thorns starfish, a large, multiple-armed starfish
See also
- COT (disambiguation)