Butler County is a county located in the southeast Ozark Foothills Region in the U.S. state of Missouri. As of the 2020 Census, the county's population was 42,130. The largest city and county seat is Poplar Bluff. The county was officially organized from Wayne County on February 27, 1849, and is named after former U.S. Representative William O. Butler (D-Kentucky), who was also an unsuccessful candidate for Vice President of the United States. The first meeting in the Butler County Courthouse was held on June 18, 1849.

Butler County comprises the Poplar Bluff, MO Micropolitan Statistical Area.

Geography

According to the U.S. Census Bureau, the county has a total area of , of which is land and (0.6%) is water.

Adjacent counties

  • Wayne County (north)
  • Stoddard County (northeast)
  • Dunklin County (southeast)
  • Clay County, Arkansas (south)
  • Ripley County (west)
  • Carter County (northwest)

Major highways

National protected area

  • Mark Twain National Forest (part)

Demographics