Bonifacio Ondó Edú-Aguong (19 March 1922 – 5 March 1969) was an Equatoguinean politician who served as the Prime Minister of Equatorial Guinea from 1964 to 1968 while it was still under Spanish colonial rule, as Spanish Guinea. He played a leading role in the country's independence, and led the National Unity Movement of Equatorial Guinea from 1959 until his death.

He took office when the country gained autonomy in 1964, and ran in the country's first presidential election in 1968, losing in the run-off. He handed power over to the newly elected president Francisco Macías Nguema on 12 October 1968 (the day of independence). He was imprisoned and officially committed suicide only a few months later. Another account says he returned in 1969 from exile in Gabon and was killed. a member of the Fang people, was born in either 1920 or 1922,