Blantyre is Malawi's second-largest city.
Blantyre may also refer to:
- Blantyre District, of which the city is the capital
- Blantyre, South Lanarkshire, a town in Scotland
- Blantyre (ward), a local electoral division
- Blantyre, Queensland, an Australian hamlet
- Blantyre (estate), Massachusetts, United States
- Blantyre, Toronto, part of Birch Cliff, a Canadian neighbourhood
See also
- Blantyre House, a disused English prison and former mansion
- Lord Blantyre, a title of nobility in the Peerage of Scotland