Biobío or Bio-Bío (older form: Bío-Bío) may refer to any of the following:

  • Biobío River, the second longest river in Chile and the former southern frontier of the Captaincy General of Chile

; Administrative divisions:

  • Biobío Region, eighth region of Chile (first level)
  • Biobío Province, subdivision of the Bío-Bío Region (second level)
  • Alto Biobío, commune of the Bio Bío Province (third level)

See also

  • Radio Bío-Bío, a Chilean radio station with a news-based output
  • ST Bio Bio, an Argentinian tug