thumb|270px|Greifswalder Bodden in the center of the map
The Bay of Greifswald or Greifswald Bodden () is a basin in the southwestern Baltic Sea, off the shores of Germany in the state of Mecklenburg-Vorpommern. With an area of 514 km², it is the largest Bodden of the German Baltic coast.
To the west is the island of Rügen; to the southeast, the island of Usedom; to the east, the Bay of Pomerania, and to the south, the German mainland. The bay is also joined to the Baltic Sea through the Strelasund, a narrow sound separating Rügen from the mainland. The bay's northern end is sometimes called the Rügischer Bodden.
The bay itself has a heavily indented coastline, making it a bay of bays. The headlands of Mönchgut (in east Rügen) and Zudar (in south Rügen) – the former actually being made up of several peninsulae – subdivide the bay into many smaller bays. The bay's main port is Greifswald. Amongst the islands in the east of the bodden are Vilm, Koos, Riems and the former island of Stubber, now a sandbank.
The Bay of Greifswald is quite shallow, with an average depth of 5.6 m, and a maximum depth of 13.5 m. ranging from 5.3 and 12.2 psu.