thumb|An [[Eastern Orthodox Church|Eastern Orthodox cross]]

April 21 - Eastern Orthodox liturgical calendar - April 23

All fixed commemorations below are observed on May 5 by Eastern Orthodox Churches on the Old Calendar.

For April 22nd, Orthodox Churches on the Old Calendar commemorate the Saints listed on April 9.

Saints

  • Holy Apostle Nathaniel of the Twelve (Bartholomew) (1st century)
  • Apostles Apelles, Luke (not the Evangelist), and Clement, of the Seventy (1st century)
  • Martyr Nearchus, by fire (3rd century)
  • Venerable Theodore the Sykeote, Bishop of Anastasiopolis in Galatia (613)