Aisén or Aysén may refer to:
Places
- Aysén, Chile, a commune in Aysén Province
- Aysén Region, one of Chile's administrative divisions
- Aysén Province, a province in the Chilean region
- Puerto Aysén, the capital city of Aysén Province
People
- Aisén Etcheverry, chilean lawyer and Science, Technology, Knowledge and Innovation Minister