Accomac may refer to:
Geography
- Accomac, Virginia, a town in Virginia
- Accomac Shire, a former county in Virginia of which the town was the county seat
- Accomac, Pennsylvania
Peoples
- Accomac people, a historic Native American tribe from the Eastern Shore of Virginia
Ships
- , three ships of the US Navy
See also
- Accomack County, Virginia, the current incarnation of Accomac Shire
- Plymouth, Massachusetts was built on a site identified on early maps as Accomack