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The following lists events that happened during 1901 in South Africa.

Incumbents

Cape Colony

  • Governor of the Cape of Good Hope and High Commissioner for Southern Africa:Alfred Milner then Walter Hely-Hutchinson (governor from 6 March but not high commissioner).
  • Prime Minister of the Cape of Good Hope: John Gordon Sprigg.

Natal

  • Governor of the Colony of Natal: Charles Bullen Hugh Mitchell (until 6 May), Henry Edward McCallum (starting 6 May).
  • Prime Minister of the Colony of Natal: Albert Henry Hime.

Orange Free State

  • State President of the Orange Free State: Martinus Theunis Steyn.
  • Administrator of British-occupied Orange River Colony and UK High Commissioner for Southern Africa: Alfred Milner, 1st Viscount Milner.

South African Republic

  • State President of the South African Republic: Paul Kruger (in exile); Schalk Willem Burger (acting).
  • Administrator of British-occupied Transvaal and UK High Commissioner for Southern Africa: Alfred Milner, 1st Viscount Milner.

Events

;January

  • 9 &ndash; Herbert Kitchener reports that Christiaan de Wet has shot a British peace envoy and flogged two more who had gone to his commando to ask the Burghers to halt fighting.
  • 15 &ndash; HMS Sybille, a 3,400-ton , strikes a reef about south of Lamberts Bay.
  • 31 &ndash; General Jan Smuts and his commandos capture Modderfontein.

;February

  • 1 &ndash; Bubonic plague breaks out in Cape Town.
  • 26 &ndash; The Middelburg peace conference fails as Boers continue to demand autonomy.

;May

  • 31 &ndash; Officially unrecognized Zulu king Dinuzulu kaCetshwayo refuses British instructions to take up arms against the Boers.

;June

  • 18 &ndash; Emily Hobhouse reports on the high mortality and cruel conditions in the Second Boer War concentration camps
  • 25 &ndash; Boer armies invaded the Cape Colony and attacked the British settlement of Richmond for a day, then retreated as British forces approached.

;July

  • 2–6 &ndash; Nine Boer prisoners-of-war are murdered by Australian members of the Bushveldt Carbineers in the Spelonken area near Louis Trichardt.
  • 16 &ndash; The Fawcett Commission is established to look at living conditions of women and children, including water supply, sanitation, medical care and the mortality and birth rates in the concentration camps.

;August

  • 4 &ndash; Lieutenant-general Paul Methuen destroys the village of Schweizer-Reneke under the British scorched earth policy.
  • 20 &ndash; General Koos de la Rey's 84-year-old mother is sent to a concentration camp at Klerksdorp.

;September

  • 17 &ndash; Commandant-General Louis Botha and General Cecil "Cherry" Cheere Emmett join forces to invade Natal.

;October

  • Mahatma Gandhi embarks at Durban for Mauritius en route to Bombay.

;November

  • 1 &ndash; Standard Bank opens its second branch in Johannesburg on Eloff Street.
  • 9 &ndash; The electric tramline in Cape Town is extended from Sea Point to Camps Bay.
  • 18 &ndash; Boer commandos invade the Cape Colony and come to within 50 miles of Cape Town.

;December

  • 22 &ndash; On Peace Sunday Charles Frederic Aked (1864–1941), a Baptist minister in Liverpool, says: "Great Britain cannot win the battles without resorting to the last despicable cowardice of the most loathsome cur on earth; the act of striking a brave man's heart through his wife's honour and his child's life. The cowardly war has been conducted by methods of barbarism... the concentration camps have been Murder Camps." A crowd follows him home and breaks the windows of his house.
  • 27 July &ndash; Natal &ndash; Mtwalume to North Shepstone, .

Locomotives

;Cape

  • Six new Cape gauge locomotive types enter service on the Cape Government Railways (CGR):
  • Six 4-4-0 3rd Class Wynberg Tender locomotives in suburban service in Cape Town.
  • Eight redesigned American-built 6th Class 4-6-0 steam locomotives. In 1912 they would be designated South African Class 6G 4-6-0| on the South African Railways (SAR).
  • The first of sixteen 8th Class 2-8-0| Consolidation type locomotives. In 1912 they would be designated Class 8X on the SAR.
  • The Namaqua Copper Company acquires its first locomotive, a 0-4-2 saddle-tank shunting engine named Pioneer.

;Natal

  • The Natal Government Railways (NGR) rebuilds one of its Class G tank locomotives to a Class H Pacific wheel arrangement. In 1912 it would be designated Class C1 on the SAR.
  • The Zululand Railway Company, contracted for the construction of the line from Verulam to Tugela River, acquires one 2-6-2 tank locomotive.