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The following lists events that happened during 1858 in South Africa.
Incumbents
- Governor of the Cape of Good Hope and High Commissioner for Southern Africa: Sir George Grey.
- Lieutenant-governor of the Colony of Natal: John Scott.
- State President of the Orange Free State: Jacobus Nicolaas Boshoff.
- President of the Executive Council of the South African Republic: Marthinus Wessel Pretorius.
Events
;March
- 19 – Senekal's War breaks out between the Orange Free State and the Basotho tribe.
Births
- 6 December – Ernest Edward Galpin, botanist and banker. (d. 1941)
Deaths
- Cornelius Kok II, leader of the Griqua people. (b. 1778)
