<!-- "none" is preferred when the title is sufficiently descriptive; see WP:SDNONE -->
The year 1627 in science and technology involved some significant events.
Astronomy
- Johannes Kepler's Rudolphine Tables are published.
Exploration
- January – The Dutch ship t Gulden Zeepaert, skippered by François Thijssen, sails along the south coast of Australia.
Medicine
- Adriaan van den Spiegel's ' is published posthumously in Venice with illustrations by Giulio Casserio.
- Gaspare Aselli's ' is published posthumously in Milan.
Publications
- Francis Bacon's , or A Natural History and New Atlantis are published posthumously.
Births
- January 25 – Robert Boyle, Anglo-Irish chemist (died 1691)
- November 29 – John Ray, English naturalist (died 1705)
Deaths
- February 22 – Olivier van Noort Dutch circumnavigator (born 1558)
- July 20 – Guðbrandur Þorláksson, Icelandic mathematician and cartographer (born 1541)
- October 21 – Frederick de Houtman, Dutch explorer (born 1571)
