thumb|250px|[[November 10: Outnumbered Christian crusaders overwhelmed by Ottoman Muslims at the Battle of Varna after King Wladyslaw leads attack on the camp of the Sultan Murad. (painting by Stanisław Chlebowski.)]]
Events
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January–March
- January 2 – The Battle of Kunovica is fought between the Christian crusaders, led by John Hunyadi, and the Muslim armies of the Ottoman Empire in what is now Serbia. After having retreated 10 days earlier following their loss in the Battle of Zlatitsa, Hunyadi and King Wladyslaw III of Hungary defeat the Ottoman forces and take several of their commanders as prisoners of war, including Mahmud Bey, son-in-law of the Sultan Murad II.
- February 15 – Stjepan Vukčić Kosača, the Grand Duke of Bosnia, signs a treaty with the King Alfonso of Naples, agreeing to become his vassal in exchange for help against the Republic of Venice.
- March 2 – The League of Lezhë, an alliance of Albanian principalities, is established in Lezhë; George Kastrioti Skanderbeg is proclaimed commander of the Albanian resistance.
April–June
- April 15 – King Wladyslaw of Hungary appears before the Országgyűlés, the Diet of Hungary in Buda, and pledges to the legislators present that he will lead the attack against the Turkish Muslims in the summer.
- April 18 – In Sicily, the University of Catania receives papal recognition from Pope Eugene IV, ten years after its founding on October 19, 1434.
- May 22 – The Treaty of Tours, signed between England and France, secures a truce in the Hundred Years' War for five years.
- June 15 – Cosimo de' Medici founds a public library at San Marco, Florence.
- June 29 – Battle of Torvioll: Skanderbeg defeats an Ottoman army.
July–September
- July 22 – Oddantonio da Montefeltro, the Duke of Urbino, an independent duchy in what is now the Le Marche region of Italy, is assassinated at his palace by conspirators, who also murder his counsellors Manfredo dei Pio da Carpi and Tommaso di Guido dell'Agnello. He is succeeded by his half-brother, Federico da Montefeltro.
- August 6 – A Portuguese fleet of caravels, led by Lançarote de Freitas, lands 235 slaves at Algarve, Portugal.
- August 15 – The Peace of Szeged is signed between the Turkish Ottoman Empire and Hungary.
- August 22 – Đurađ Branković reclaims Serbia from Ottoman control after the signing of the peace of Szeged, and Wladyslaw of Hungary offers the throne of Bulgaria to John Hunyadi.
- September 9 – General Alvise Loredan, commander of the Venetian and Papal States squadrons in the Crusade of Varna, receives instructions from the Republic of Venice to open secret negotiations with the Ottoman Sultan and to abstain from offensive actions until further notice. Loredan is soon faced with defending an Ottoman invasion of Europe.
- September 18 – As the Crusade of Varna resumes, the 16,000 Christian soldiers under the command of Wladyslaw and Hunyadi begin crossing over the Danube river near Belgrade and complete their crossing into Ottoman Muslim territory in Bulgaria.
October–December
- October 20 – As the Christian crusaders begin their approach to the Black Sea, the former Ottoman Sultan Murad II comes out of retirement at Bursa to assume command of the Ottoman troops.
Date unknown
- Constantine XI Palaiologos, as ruler of the Despotate of the Morea, invades the Duchy of Athens (at this time under Florentine control), and forces it to pay tribute and return Thebes to the Byzantine Empire.
- Forces of the Sultan of Egypt fail to take Rhodes from the Knights of Rhodes.
- Portuguese explorers reach the mouth of the rivers Senegal and Gambia.
- The first European slave market for the sale of African slaves, the Mercado de Escravos, opens in Lagos, Portugal.
- A serious fire occurs at Old St Paul's Cathedral in London.
- The Iguvine Tablets are discovered at Gubbio, Italy.
- Stephen II of Moldavia takes as co-ruler his step brother Petru, also brother-in-law to John Hunyadi.</onlyinclude>
Births
- January 24 – Galeazzo Maria Sforza, Duke of Milan (d. 1476)
- March 15 – Francesco Gonzaga, Catholic cardinal (d. 1483)
- April 22 – Elizabeth of York, Duchess of Suffolk (d. 1503)
- May 29 – Otto III, Duke of Pomerania-Stettin (1460–1464) (d. 1464)
- June 14 – Nilakantha Somayaji, Indian astronomer-mathematician (d. 1544)
- June 28 – Charlotte, Queen of Cyprus (d. 1487)
- October 18 – John de Mowbray, 4th Duke of Norfolk (d. 1476)
- date unknown – Donato Bramante, Italian architect (d. 1514)
Deaths
- January 8 – Wilhelm II, Count of Henneberg-Schleusingen (b. 1415)
- February 14 – Henriette, Countess of Montbéliard, regent of Württemberg (b. 1387)
- March 9 – Leonardo Bruni, Italian humanist (b. 1374)
- April 26 – Robert Campin, Flemish painter (b. 1378)
- May 20 – Saint Bernardino of Siena, Italian Franciscan missionary (b. 1380)
- May 27 – John Beaufort, 1st Duke of Somerset, English military leader (b. 1404)
- October 15 – Niccolò Piccinino, Italian mercenary (b. 1386)
- November 10 – King Władysław III of Poland (in battle) (b. 1424)
- November 25 – Martin Gouge, French chancellor
- date unknown – Pier Paolo Vergerio the Elder, Italian humanist, statesman, and canon lawyer