Ōsumi can stand for:

  • Ōsumi Province, a former province of Japan
  • Ōsumi Peninsula
  • Ōsumi Islands, an archipelago at the northern end of the Ryukyu Islands
  • Ōsumi (satellite), the first Japanese satellite
  • Ōsumi class LST, a class of Japanese amphibious transport dock

People with the surname

  • Masaaki Ōsumi (born 1934), Japanese anime director
  • Baron Mineo Ōsumi, a Japanese admiral
  • Paul Osumi, a Japanese Christian minister
  • Yoshinori Ohsumi, Japanese cell biologist and 2016 Nobel laureate in Physiology or Medicine