Água Grande is a district of São Tomé and Príncipe, on São Tomé Island. Its capital, São Tomé, is also the national capital of the equatorial Atlantic island nation of São Tomé and Príncipe. Covering only , it is the smallest of the nation's seven districts in terms of area, but the largest in population with 69,454 residents in 2012 rising to an estimated 77,700 in 2018. It is divided into the two statistical subdistricts São Tomé and Pantufo.
| data1 = 8407
| label2 = 1950
Persons
- Marcos Barbeiro, footballer
- Guadalupe de Ceita, medic and a politician
- Manuel Pinto da Costa, politician, President of São Tomé and Príncipe from 2011 to 2016
- Adimar Neves, footballer currently living in Europe
- Lecabela Quaresma, athlete
International relations
Água Grande District is twinned with:
- Lisbon, Portugal